Welcome
About us
Gaël Chételat’s team “Multimodal neuroimaging and Lifestyle in Aging and Alzheimer’s disease” is working with complementary neuroimaging tools and neuropsychological assessments to improve understanding of Alzheimer’s disease physiopathological mechanisms and of determinants of mental health and well-being in the ageing population.
The team uses structural and functional MRI (T1, FLAIR, T2, resting-state fMRI, task-related fMRI, DKI, ASL, high-resolution hippocampal T2, etc.) in people ranging from cognitively normal young to elderly people to patients at various stages of Alzheimer’s disease and others neurodegenerative diseases.
The team is also coordinating a European programme including non-pharmacological interventions through mental training (meditation and English learning) in ageing
Research Project
Meditation
Mental training for stress reduction and emotion regulation through meditation practice appears as a promising alternative to improve mental…
Lifestyle
The Lifestyle research group aims at understanding the brain mechanisms underlying the effects of lifestyle factors from normal aging to Alzheimer’s disease dementia…
Subjective Cognitive Decline
Subjective cognitive decline Why studying SCD in the context of Alzheimer’s disease?One of the main challenges in AD research is to detect the disease as…
Hippocampal Subfields
Hippocampal subfield Hippocampal atrophy is well-known as an early biomarker of AD, but it lacks specificity as it is also observed in many different situations…
Multimodal NeuroImaging
Multimodal NeuroImaging Why multimodal neuroimaging? Multimodal imaging provides a unique opportunity to investigate the temporal and…
Blood Biomarkers
The Age-Well study offers a unique set of complementary assessments including blood markers (general health, emotions, stress, ageing and Alzheimer’s disease) but also detailed cognitive…
Psychoaffective factors
As no effective treatment has been found yet, one of the main challenges in Alzheimer’s disease (AD) research is to work on (i) preventing…
Sleep quality
In the Silver Santé Study, my group investigates how sleep quality, assessed using different tools (questionnaires, actigraphy…
Advanced Neuroimaging Processing
In addition to voxel-wise (volume) analyses, we are developing or optimizing surface-based analyses on the cortical surface…